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KMID : 0385219970070010094
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Korean Journal of Gerontology
1997 Volume.7 No. 1 p.94 ~ p.102
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Unique Contributions of Longitudinal Studies of Aging for Detection and Prevention of Age-Associated Disease and Functional Decline
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Fozard James-L.
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Abstract
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Aging is a very individual matter. Longitudinal studies provide the best way to characterize how physiological and behavioral processes change over time. A major goal of longitudinal studies should be to describe individual differences in levels and rates of change in aging processes. Knowing when and how much aging processes change over time is a powerful tool for identifying transitions between normal aging and disease and can be useful in identifying persons at risk for age associated diseases and for planning therapeutic interventions. Examples from the National Institute on Aging Baltimore Longitudinal Study of Aging (BLSA) and other longitudinal studies will be given to illustrate these conclusions. The examples include transitions from childhood to adulthood and various stages of the adult life cycle. The usefulness of longitudinal studies in contemporary research depends both on research data collected and the preservation of biological specimens useful for analyses in clinical as well as genetic laboratories.
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KEYWORD
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longitudinal studies aging and disease
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